By Connie Henke Yarbro, Margaret Hansen Frogge, Michelle Goodman

ISBN-10: 0585352747

ISBN-13: 9780585352749

ISBN-10: 0763702196

ISBN-13: 9780763702199

The Fourth variation of melanoma Nursing is revised and up-to-date to comprise the most recent advancements in oncology nursing and melanoma sufferer care. The easy technological know-how chapters partially i've been thoroughly reorganized and rewritten to mirror the large elevate over the past few years in medical wisdom concerning the courting among genes and melanoma. each bankruptcy has been up to date with a spotlight on self-care, controlled care, and ambulatory care and new chapters, ''Health coverage and Legislative Issues'' and ''The position of the complicated perform Nurse'' were additional. also, there are multiplied sections on bone marrow transplantation urologic tumors and survivorship. As with the former versions, melanoma Nursing maintains to give the main entire details on oncology nursing with an in depth artwork application and references from major melanoma nursing specialists.

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Additional info for Cancer Nursing: Principles and Practice

Sample text

It is thought that most human cancers result from a combination of genetic changes that must include both the absence of the protein products of cancer-suppressor genes and the presence of abnormal products of oncogenes. It is likely that for each "upregulating" function coded by an oncogene there is a balancing "down-regulating" function coded by a cancer-suppressor gene. @l* This down-regulating antioncogene system is at least as complicated as the upregulating oncogene system, but it is only beginning to be understood.

Huggins CB: Endocrine-induced regression of cancers. Science 156:1050-1054, 1967 17. Roentgen WC: Uber eine neue Art von Strahlen. -med, Gesekch. Wunb 132-141j, 1895 18. Coutard H: Roentgen therapy of epitheliomas of the tonsillar region, hypopharynx, and larynx from 1920 to 1926. Am JRmntgend 28:313-331, 1932 19. Frieben A. Demonstration lines cancroids des rechten Handruckens, das sich nach langdauernder Einwirkung von Roentgenstrahlen entwichelt hatte. Fortschr Geb Rmtgenstr6: 106, 1902 20. Von Jagic N, Scwarz G, von Siebenrock L Blutbefunde bei Roentgenologon.

This ~ ~ ~gene * codes for a transcription factor that, in the form of a dimer or tetramer, binds ~pecifically~~ to DNA and mediates RNA synthesis. Originallyidentified in cells transformed by simian virus 40 and thought to be an oncogene product because mutant forms exerted a dominant transforming effect on cells, p53 finally has been recognized as a cancer-suppressor gene product. H0 "THE GUARDIAN OF THE GENOME" The p53 cancer-suppressor gene is the most important one so far discovered. Not only is it the most frequently mutated, but when it is not mutated, as is the case in CHAPTER 1 Milestones in Our Understanding of Cancer is hardly new.

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Cancer Nursing: Principles and Practice by Connie Henke Yarbro, Margaret Hansen Frogge, Michelle Goodman


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