By Noel Keen, Brian Staskawicz, John Mekalanos, Frederick Ausubel, R. James Cook (Eds.)

ISBN-10: 0309070805

ISBN-13: 9780309070805

ISBN-10: 0309570018

ISBN-13: 9780309570015

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Woestyn, S. & Cornelis, G. R. (1996) Mol. Microbiol. 20, 255–262. 73. Anderson, D. M. & Schneewind, O. (1999) Mol. Microbiol. 31, 1139–1148. 74. Mudgett, M. B. & Staskawicz, B. J. (1999) Mol. Microbiol. 32, 927–941. 75. Huynh, T. , Dahlbeck, D. & Staskawicz, B. J. (1989) Science 245, 1374–1377. 76. , Burr, T. , Mansfield, J. , Vivian, A. & von Kietzell, J. (1997) Pseudomonas syringae Pathovars and Related Pathogens (Kluwer, Dordrecht, The Netherlands), p. 663. 77. , Boucher, C. & Arlat, M. (1998) Mol.

YopH dephosphorylates proteins from the focal adhesion (PTPase, phosphotyrosine phosphatase); YopE inactivates Rac and cdc42 by stimulating their GTPase activity (GAP, GTPaseactivating protein); YopT deactivates RhoA. YopM is a strongly acidic protein containing leucine-rich repeats (LRRs) whose action and target remain unknown. It belongs to a growing family of type III effectors that has several representatives in Shigella (ipaH multigene family) and Salmonella (48). YopM has been shown to traffic to the cell's nucleus by means of a vesicle-associated pathway (49), but its action in the nucleus remains unknown.

Staskawicz, B. J. (1993) Mol. Gen. Genet. 239, 6–10. 61. Kim, J. , Charkowski, A. , Alfano, J. , Collmer, A. & Beer, S. V. (1998) Mol. Plant–Microbe Interact. 11, 1247–1252. 62. , Ott, P. , Kecskes, M. L. & Klement, Z. (1999) Physiol. Mol. Plant Pathol. 55, 215–223. 63. Mushegian, A. , Fullner, K. , Koonin, E. V. & Nester, E. W. (1996) Proc. Natl. Acad. Sci. USA 93, 7321–7326. 64. , Sansonetti, P. J. & Parsot, P. (1993) Infect. Immun. 61, 1707–1714. 65. Dijkstra, A. J. & Keck, W. (1996) J. Bacteriol.

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Colloquium on Virulence and Defense in Host—Pathogen Interactions: Common Features Between Plants and Animals by Noel Keen, Brian Staskawicz, John Mekalanos, Frederick Ausubel, R. James Cook (Eds.)


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