By John G. Kemeny, J. Laurie Snell, Anthony W. Knapp

ISBN-10: 0387901779

ISBN-13: 9780387901770

ISBN-10: 3540901779

ISBN-13: 9783540901778

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20) where φ( ) is the standard normal density function. These results suggest the following corrected p-value approach. For all γ in the range [X(nε) , X(n(1−ε))] we compute either the Wald, score or likelihood ratio test pvalue. Let Pmin be the smallest of these p-values over the range of threshold parameters. P. -T. 21) where z = Φ −1 (1 − Pmin /2) with Φ the standard normal distribution function. Table 1 shows the results of the various methods of testing for an age effect in the BMT data. Here we see that if no correction is made then there is a highly significant age effect.

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General definition of residuals (with discussion). J. Roy. Statist. Soc. B 30, 248–275. B. (1986). Dichotomizing a continuous covariate in the Cox regression model. Statist. Res. Unit Univ. Copenhagen Res. Report 86 (2). L. (2003). Survival Analysis: Techniques for Censored and Truncated Data, 2nd edn. Springer, New York. , Schumacher, M. (1996). Evaluating the effect of optimized cutoff values in the assessment of prognostic factors. Comput. Statist. Data Anal. 21, 307–326. , Schumacher, M. (1992).

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