By Domenico Coppola

ISBN-10: 9048137241

ISBN-13: 9789048137244

This quantity is a part of a ebook sequence that was once first released in 10-volumes through Kluwer in 1989 lower than the sequence editorship of Professor Hans E. Kaiser, D.Sc., former Professor of Pathology on the college of medication, college of Maryland at Baltimore, MD, united states besides different leaders within the box of melanoma. with a purpose to surround the starting to be physique of information on a number of points of melanoma progress and development seeing that then, the sequence has now been extended to 17 volumes.

This quantity is a complete replace at the mechanisms of tumorigenesis, and contains the advances within the box, as supplied by means of the latest molecular options (microarray, proteomic, and different omics). whereas the 1st section of the ebook comprises chapters discussing pediatric melanoma, the impact of environmental components and oncogene task in tumorigenesis, the second one element of the ebook is based through organ websites (Esophagus, Breast, Pancreas, Colon, Lung, Prostate, epidermis, mind, Endocrine procedure, Lymphoid approach, Bone, Head and Neck, and Cervix). This layout offers the reader with easy accessibility to the wanted information.

This definitive textual content will provide the doctors, even if in study, academia or scientific perform, the newest details counseled via the area popular members. The huge diversity of themes will make this a valued reference and supply a wealth of data, making this a "state of the technological know-how" on carcinogenesis.

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New PDF release: Mechanisms of Oncogenesis: An update on Tumorigenesis

This quantity is a part of a e-book sequence that was once first released in 10-volumes by means of Kluwer in 1989 lower than the sequence editorship of Professor Hans E. Kaiser, D. Sc. , former Professor of Pathology on the university of drugs, college of Maryland at Baltimore, MD, united states in addition to different leaders within the box of melanoma.

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Extra info for Mechanisms of Oncogenesis: An update on Tumorigenesis (Cancer Growth and Progression)

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Topalian, S. L. and Berzofsky, J. A. Clinical trial designs for the early clinical development of therapeutic cancer vaccines, J Clin Oncol 19: 1848±54, 2001. , Coulie, P. , Brichard,V. , Renauld, J. C. and Boon, T. Genes coding for tumor antigens recognized by cytolytic T lymphocytes, Immunol Rev 145: 229±50, 1995. 13 Rosenberg, S. A. Cancer vaccines based on the identification of genes encoding cancer regression antigens, Immunol Today 18: 175±82, 1997. 14 Van den Eynde, B. J. and van der Bruggen, P.

MIIC, MHC class II compartment 62 mimicry, molecular 211, 222, 224 mimotopes 44 mitogen-activated protein kinases (MAPKs) 270 ff. mixed lymphocyte tumor cell culture (MLTC) 41 f. MLTC see mixed lymphocyte tumor cell culture MMPs see matrix metalloproteinases Mo-DCs 184±193 mobilization, DC 183 models ±, animal 230 ±, of tumors 218±221 ±, T-body approach 292 f. modulation of the expression of HSPs 261 f. modulation of the site of HSP expression 262 f. molecular mimicry 211, 222 ±, definition 224 monitoring ±, CTL responses 44±49 ±, immunoresponses 194 f.

MHC class II-associated Ii peptide (CLIP) 62 MHC class II expression ±, antitumor response 82 f. ±, modulation of immune response 81 f. MHC class II-restricted T cell epitopes 232 MHC class II transactivator (CIITA) 81±84 MHC haplotypes 215, 222 MHC locus 59 microenvironment 47 ±, tumor 311, 327 MIF see macrophage migration inhibitory factor migration, dendritic cells 180 f. MIIC, MHC class II compartment 62 mimicry, molecular 211, 222, 224 mimotopes 44 mitogen-activated protein kinases (MAPKs) 270 ff.

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Mechanisms of Oncogenesis: An update on Tumorigenesis (Cancer Growth and Progression) by Domenico Coppola


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