By Icon Health Publications

ISBN-10: 058543073X

ISBN-13: 9780585430737

ISBN-10: 0597831335

ISBN-13: 9780597831331

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Extra info for The Official Patient's Sourcebook on Uterine Fibroids

Sample text

Some local medical societies offer lists of member doctors. Again, these lists do not have information on the quality of care that these doctors provide. Additional steps you can take to locate doctors include the following: · Check with the associations listed earlier in this chapter. org. This Web site is run by “Administrators in Medicine,” a group of state medical board directors. · The American Board of Medical Specialties can tell you if your doctor is board certified. “Certified” means that the doctor has completed a training program in a specialty and has passed an exam, or “board,” to assess his or her knowledge, skills, and experience to provide quality patient care in that specialty.

3 expression in mouse uterine myocytes at different times in gestation using the patch clamp technique and immunohistochemical assays. 3 protein will be used to knock-down Na/+ channel current. 3 channel in native uterine myocytes from non-pregnant mice will be performed. 23 protein underlies the observed Na/+ current and will help elucidate its role in the regulation of uterine contraction at term. While pre-term labor is a major health problem given the risk it carries with respect to birth defects and costs associated with premature delivery, a better understanding of the regulation of uterine contraction can only improve our ability to pharmacologically manage this problem.

Electrophysiological reports have shown that myometrial cells contain a variety of K+ channel types that may be potential therapeuric targets, including the large-conductance calcium-activated K+ channel (BKCa channel). Blockage of BKCa Studies 43 channels depolarizes myometrial cells and increases contractile activity while activation of these channels by agonists and beta-adrenergic agents induces potent uterine relaxation. Interestingly, the activation of the BKCa channel by phosphorylating agents, Ca2+, or voltage is dependent on whether it is isolated from non-pregnant or pregnant tissue.

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The Official Patient's Sourcebook on Uterine Fibroids by Icon Health Publications


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