By Khorshed M. Pavri

ISBN-10: 8123701756

ISBN-13: 9788123701752

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This, however, is the very cell that HIV has chosen as its major target. The entire immune system—not only the infected CD4 cells—ultimately come under the attack of HIV. No doubt, during the very early phase of HIV infection, an effective immune response is mounted against HIV since CD4 and various other cells are not much affected. In most acute viral infections, such a response is enough to eliminate the virus from the system.

THE VIRUS AND THE TESTS 41 Situation in India In India, ELISA is the most widely used test with Western blot as a confirmatory test. During the early phase of the epidemic, this strategy worked out satisfactorily. However, with the increase in the number of seropositives, the expensive confirmatory test now needs to be performed on a much larger number. Therefore, alternative strategies have been developed on the general principles recommended by the WHO, also keeping in mind our culture and socio-economic conditions.

Oral cavity or the mouth). Once the germs have sneaked in, they roam around and attack (infect) their favourite target system, namely, respiratory, gastrointestinal, etc. Macrophages : Within the body, the first encounter of the 52 . CHALLENGE OF AIDS Fig. 17 : Major cellular components of the immune system. foreign invader is with macrophages and their precursors called monocytes. Macrophages are highly mobile cells which may be termed 'scavengers' because they clean up the system by engulfing the invaders in an attempt to get rid of them.

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Challenge of AIDS by Khorshed M. Pavri

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